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This suppresses the production of several pro-inflammatory compounds, dampening the inflammatory response at its sourcewithout the broad immunosuppressive effects that come with steroids

The arginine substitution and extended N-terminus confer reduced affinity for IGFBPs, allowing greater bioavailability and receptor interaction

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First-line atezolizumab plus nab-paclitaxel for unresectable, locally advanced, or metastatic triple-negative breast cancer: IMpassion130 final overall survival analysis