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Growth/differentiation factor-15 (GDF-15) Another potential therapeutic pathway for obesity pharmacotherapies is through the stress-induced cytokine GDF-15, which is expressed in multiple cell types including cardiomyocytes, adipocytes and macrophages [98]

Folates in children with Down syndrome and the impact of dietary supplementation

To advance translational applications, future studies should focus on: (1) transforming dynamic biomarkers into clinical decision-making tools, such as evaluating early changes in circulating mitochondrial-derived vesicles or oxidative stress markers (e.g., 8isoprostaglandin F2 (8-iso-PGF2))to predict subsequent biochemical and histological responses

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Its genome is a single-stranded positive-sense RNA that contains four structural proteins: spike protein (S), membrane protein (M), nucleocapsid protein (N) and envelope protein (E) (121)