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NICE guidance (NG28) recommends: Consider reducing sulfonylurea or insulin doses when starting Ozempic to mitigate hypoglycaemia risk, with adjustments guided by blood glucose monitoring Maintaining metformin at existing doses unless contraindicated Reviewing all medications that affect glucose metabolism Never stopping insulin abruptly , as this could lead to diabetic ketoacidosis (DKA) Lifestyle optimisation enhances Ozempic's effectiveness

Boris Kandinov et al

It also increases fertility and treats muscle weakness and heart muscle problem

The Food and Drug Administration label for semaglutide the active ingredient in many weight loss drugs says it may increase the risk of bone fractures in older adults and women

GLP-1 RA Therapy for Alcohol Use Disorder