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Acknowledgements The authors are grateful for the support received from the Austrian Science Fund (FWF, P 29379-B28), the Tyrolean Science Fund (TWF, 0404/1812), the Austrian Society of Gastroenterology and Hepatology (GGH) and the European Crohns and Colitis Organisation (ECCO) (to T.E.A.)

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Loza-Medrano et al

Pickart 2008, 2015 : narrative reviews on GHK-Cu, founded on a compilation of in vitro and animal studies with few randomised clinical trials

The glucagon receptor response and the thermogenic effects it produces may be less susceptible to the receptor desensitization that affects GLP-1 pathways