Keep out of the reach of children
Animals presenting EAU are randomized and distributed into three groups: (1) the untreated EAU control (n = 11), (2) the test compound treated group (n = 7), such as EC1669, (3) the test compound and competitor compound treated group (n = 7), such as EC1669 plus EC0923, and (4) the positive control treated group (n = 7), such as methotrexate (MTX)
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To this solution is added the thiophilic agent in organic solvent EC1579 (200mg, l.Oeq) was dissolved in degassed (Ar bubbling) 20mM P0 4 pH7 buffer (4.0mL) and added dropwise to a stirring solution of crude EC0469 (80mg, l.Oeq) in dry dimethylsulfoxide (4.0mL, Aldrich) at room temperature with Ar bubbling