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This leads to increased levels of insulin-like growth factor 1 (IGF-1), which is crucial for fat metabolism and overall health

Taken together, the researchers concluded that thyroid function may affect mast cells, and that mast cell degranulation could affect thyroid function.[ref] In patients with autoimmune thyroid disease, mast cells infiltrate the thyroid gland and then degranulate.[ref] Animal studies show that hypothyroidism (low thyroid hormone levels) increases the number of mast cells by up to 4.5-fold

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This protective action can help maintain your skin's natural radiance and prevent further pigmentation issues

Systemic adverse effects appear to be uncommon based on available reports, but comprehensive adverse event profiles are lacking due to the paucity of large-scale clinical investigations