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During oxidative stress, modifications in cysteine residues on Keap1 release Nrf2, allowing it to translocate into the nucleus, bind to AREs in target genes, and initiate transcription of essential antioxidant genes 67

From the study of Halme et al

Thats why she says its key that the supplement descriptions include the words hydrolyzed and peptides. The most effective formulas, she adds, are from marine sources and have about 5 grams per serving

Furthermore, repeated high-dose injections may alter the balance of antioxidants in the body, potentially triggering oxidative stress rather than reducing it

The ratio of the two forms to each other in a cell determines the status of redox reactions (chemical reactions in which one reactant transfers electrons to another reactant) in the cell