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We can basically divide these into 5 main groups

Upon transfection or transduction with genes encoding for one or multiple drug metabolizing enzyme genes, HepG2 cells have been shown to be a valuable model system to study the role of bioactivating enzymes in the cytotoxicity of toxicants (Vignati et al., 2005

The other was the control group

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase