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This condition affects the optic nerve and may lead to sudden blindness

But that improvement stopped after they stopped taking it (25)

Others may see results after a few months of use, but it is usually significant

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[21] [22] Patients with pre-existing gastroparesis or severe gastrointestinal disease were excluded from major clinical trials, and the FDA label specifically states that tirzepatide is not recommended in patients with severe gastrointestinal disease, including severe gastroparesis