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This is covered in detail in the maintenance section, but briefly: people who have established ketogenic metabolic adaptation while on semaglutide appear better positioned to maintain their weight loss after discontinuation than people who relied purely on drug-mediated appetite suppression

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Activation of these receptors generates anti-inflammatory, oxidative stress-reducing and antiatherogenic effects, which support the cardioprotective and nephroprotective effects of GLP-1 agonists (Fig

Melanomas can also occur in association with proliferative nodules