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The minor changes in estimated GFR observed with the extract are similar to those seen with furosemide Rx, supporting the idea that their mechanisms of action are comparable

Journal of Investigative Dermatology , 1999

Studies have shown that IL-17A downregulates the expression of downstream target genes in the Wnt/-catenin signalling pathway, such as AXIN2 and CCND1, in osteoblasts and osteocytes, leading to bone loss by inhibiting the activity of osteoblasts and osteocytes

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