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It has been reported that IGFBP-3 binds to a nuclear receptor, 9-cis retinoic acid receptor-alpha (RXR-), which interacts with peroxisome proliferator activated receptor-gamma (PPAR-), a nuclear protein involved in the regulation of glucose and lipid metabolism [175, 176]

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Cutting down or stopping your alcohol intake is the best way to minimise these risks. James Potter, Physician Associate When to stop drinking alcohol before surgery The answer depends on who you ask

individual results vary discuss goals and expectations with the prescribing physician