The effect of semaglutide on liver enzymes in subjects with elevated baseline alanine aminotransferase (ALT) was evaluated in a post hoc subanalysis from this trial
Studies published in January and July 2024 showed an increased risk of NAION for patients using these drugs, with individuals who took them for weight loss at an even higher risk
Stress, unhealthy eating habits, a lack of physical activity, medical comorbidities and certain medications such as diuretics, furosemide, and ritodrine can delay or impair the appetite suppression effects of semaglutide and potential weight loss
Patients particularly concerned about nausea might benefit from slower titration than standard protocols recommend, accepting that weight loss may occur more gradually
Cost - Compounded medications are typically far less expensive than brand-name versions, which is why telehealth platforms like Elevate Health can offer them at $114-$263/month versus Wegovy's $1,300+/month retail price