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Among various drug mechanisms of action, the concept of drug design based on covalent inhibition has gradually gained appreciation and utilization

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FEMS Microbiol Lett 297:217224 Ishii J, Izawa K, Matsumura S, Wakamura K, Tanino T, Tanaka T, Ogino C, Fukuda H, Kondo A (2009) A simple and immediate method for simultaneously evaluating expression level and plasmid maintenance in yeast

Springer, Berlin, pp 209229 Marjanovic A, Rozeboom HJ, Vries MS et al (2021) Catalytic and structural properties of ATP -dependent caprolactamase from Pseudomonas jessenii

Prevention begins with nervous system regulation and adequate drainage support before introducing stronger detox interventions