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Such limitations necessitate cautious interpretation when extrapolating findings from cultured astrocytes to physiological or pathological contexts

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Phosphoinositide-3-kinase The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) is an intracellular pathway involved in the regulation of a variety of critical cellular physiological processes involved in the cell cycle growth and proliferation and apoptosis, protein synthesis, and drug resistance in response to stimulation by growth factors, cytokines and hormones (Leslie and Downes 2002)

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10.1111/jcmm.15904 132 NiZ.TaoL.XiaohuiX.ZelinZ.JiangangL.ZhaoS.et al (2017)