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Temperature Control During Air Travel Semaglutide requires refrigeration between 36F and 46F (2C to 8C) before first use, and between 59F and 86F (15C to 30C) after opening for up to 30 days

Consider this scenario: a patient pauses Ozempic at 1mg for two months due to a planned surgery

Extra caution is important with: Frequent vomiting or suspected cannabinoid hyperemesis Symptoms of gastroparesis, including early fullness, nausea, vomiting, bloating, and upper abdominal pain Diabetes medications that can cause low blood sugar, including insulin or sulfonylureas Heavy cannabis use, high THC products, or unpredictable edibles dosing Prior dehydration, severe constipation, pancreatitis, or unexplained severe abdominal pain Very low appetite, unintended weight loss, or eating disorder history Multiple sedating substances Upcoming surgery, anesthesia, endoscopy, colonoscopy, or gastric emptying testing GLP-1 medications can delay gastric emptying, which also matters for procedures and anesthesia planning

This consistent weekly dosing helps maintain steady medication levels in the body, with full effects typically achieved after 4-5 weeks of regular use [5]

Acknowledgements We thank the participants of the study