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doi: 10.1016/j.bpj.2013.09.012 95 DysonF

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First, a quick refresher on what a GLP-1 receptor agonist is: one of the most popular GLP-1 receptor agonists is Ozempic, a semaglutide medication that's technically designed to help control blood sugar in people with type 2 diabetes

The expression of GCH1 induces the production of potent endogenous RTA, such as BH4/BH2, which block lipid peroxidation and ferroptosis