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Their mechanisms are complementary rather than competitive, addressing different aspects of neural plasticity: Dihexa promotes the structural formation of new synaptic connections, while PE-22-28 enhances neuronal excitability and drives neurogenesis

Individuals with DM2 are at a significantly higher risk of cognitive decline and dementia, including AD 8

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Matrix-Assisted Laser Desorption with Ionization Time-of-Flight Selection of a Suitable Matrix The second mass spectrometry technique to be used was MALDI-TOF with a reflectron (Bruker, Bremen, Germany)

Acoustic prepulses and background noise were delivered through one speaker (XT25TG30-04, Vifa), while startle stimuli were presented via the other speaker (CTS KSN-1005, Powerline)