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GRK2 mediates macrophage polarization by regulating EP4-cAMP-pCREB signaling in ulcerative colitis and the therapeutic effect of paroxetine on mice with DSS-induced colitis
Pre-treatment with XN prior to DSS exposure resulted in decreased MDA levels and COX-2 expression suggesting a protective effect against experimental colitis (101) ( Supplementary Table 1 )
However, always consult a healthcare provider before starting any new supplement
doi: 10.1016/j.ccell.2022.01.001 85 ZhangAXuYXuHRenJMengTNiYet al
In the present study, we sought to investigate whether uric acid, in the soluble form, could also activate the NLRP3 inflammasome and induce the production of IL-1
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