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In metabolically healthy individuals with intact insulin signaling, leucine-stimulated mTORC1 activation promotes anabolism without impairing insulin sensitivity, whereas in individuals with established insulin resistance, the same stimulus may exacerbate S6K1-mediated IRS-1 serine phosphorylation (12)

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Although BPC 157 had no direct effect on the proliferation of cultured tendon fibroblasts (Achilles), cell survival following H 2 O 2 stress was significantly increased