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A common feature of deep brain stimulation of the globus pallidus, an emerging efficient treatment for certain types of dystonia [258], is that it often takes weeks to months for the alleviation of symptoms to occur [259, 260]

Bibliography Sikiric P, et al

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Cholecystokinin-expressing interneurons of the medial prefrontal cortex mediate working memory retrieval

You can find further information on vitamin B12, the other micronutrients from the vitamin B group, and deficiencies, in the health field - Vitamin B deficiency