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Interestingly, probiotics or prebiotics supplementation has different and even contrary effects on the leptin signaling and food intake in genetically and diet-induced obese mice [41,42,43,44]

Painful urination or urgency : Dysuria, urgency, or suprapubic discomfort suggests urinary tract infection, which requires antibiotic treatment

The findings of subgroup analyses were similar to the overall results for each variable and revealed no significant SMD

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Wadden TA, Chao AM, Machineni S et al (2023) Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial