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In particular, folate is needed for closure of the neural tube early in pregnancy, and periconceptional supplementation with folic acid (that is, supplementation beginning one month before and continuing two months after conception) has been shown to dramatically reduce the incidence of neural tube defects (NTDs) (reviewed in 29 and 30)

Dietary Strategies to Maintain Adequate Nutrient Levels Keeping Vitamin B12 and iron levels right is key for health

Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies

Measurements change