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PMCID: PMC12231004.

Patients Taking Certain Medications Semaglutide can interact with other medications, which may affect safety and effectiveness

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Metabolic and Endocrinology Surgery Unit Unidad de Ciruga Endocrina y Metablica (UCEM) This reduction in angiotensin II levels follows the administration of GLP-1 possibly results from the increase in blood pressure values, the increased delivery of sodium to the macula densa and the reduced activity of tissue reninangiotensin-aldosterone system

Most patients experience peak nausea and vomiting during weeks 14 after starting or increasing their dose, with significant improvement by week 6