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The plate was measured spectrophotometrically at 490 nm and 680 nm wavelength (Epoch, Biotek, Bad Friedrichshall, Germany)

We interpret the clinical and mechanistic data obtained for different agents that enable weight loss and glucose control for the treatment of obesity and type 2 diabetes mellitus, respectively, by activating or blocking GIPR signalling, including the GIPRGLP1R co-agonist tirzepatide, as well as the GIPR antagonistGLP1R agonist AMG-133

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Weight-loss trajectory The question is not simply whether weight is decreasing