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There are some important caveats to note about these studies, though: First, the doses of semaglutide and tirzepatide given to participants were not equal

[1] [2] Since its introduction, Ozempic has become widely prescribed, and with increased use comes greater scrutiny of its potential side effects

These changes are enhanced by modifications in key regions such as the insular cortex (main area for taste processing) and caudate nucleus, where GLP-1-RAs are capable of normalizing altered brain activation patterns in patients with obesity and diabetes mellitus when exposed to hedonic gustatory stimuli (173, 174)

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Melas PA et al