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6.2 Phase 2 6.2.1 Edaravone (MCI-186, Radicava , Radicut , MT-1186, FAB122) Edaravone is a pyralozone free radical scavenger antioxidant that is approved by the FDA for treatment of amyotrophic lateral sclerosis (ALS)

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As a cofactor for glyceraldehyde phosphate dehydrogenase, GSH is also involved in the tricarboxylic acid cycle, glycometabolism, and protein synthesis

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Acetyl-CoA carboxylase 1 and 2 Inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis