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Oxidative damage stimulates the generation of free radicals and release high level of glutamate that may aggravate damage to brain cells 12,13
The mechanism of this combined effect appears to be sequential: TB-500 mobilizes and migrates repair cells to the injury site (via actin regulation and chemotactic signaling), while BPC-157 creates the optimal local microenvironment (via angiogenesis, growth factor expression, and NO modulation) for those cells to perform effective repair once they arrive
Neelakantan H, Wang H-Y, Vance V, Hommel JD, McHardy SF, Watowich SJ