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In standard microneedling protocols, these channels are the mechanism through which the wound healing cascade is activated

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some participants took longer to reach higher doses depending on tolerability and protocol design

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Chem Commun 55(60):1035910375 Wang Y, Wang J, Gao M, Zhang X (2015) An ultra hydrophilic dendrimer-modified magnetic graphene with a polydopamine coating for the selective enrichment of glycopeptides