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Generally acting as a tumor suppressor, ChaC2 decreases GSH levels in tumor cells, instigates mitochondrial apoptosis and autophagy via UPR and hinders tumor cell proliferation and migration in vitro and in vivo (79)
Glutathione and Liver Health: Supportive Context, Not a Shortcut Glutathione is closely tied to liver function, because the liver is a major site of antioxidant activity and detoxification
doi: 10.3389/fimmu.2019.01240 111 ChouFCChenHYKuoCCSytwuHK