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Adjusted risks for UC and CD were reported to be significantly higher in first-degree relatives of IBD patients than in those without IBD, and familial risks were highest in twins, followed by nontwin siblings, and then offspring of affected parents [16, 17]

10.1139/cjpp-2017-0559 94 RushworthG

Additionally, castration considerably decreased the expression of important antioxidant enzymes (AOEs) (GPx1, thioredoxin, SOD2, and peroxiredoxin 5) and markedly increased the expression of ROS-generating NAD(P)H oxidases

Quercetin exerts neuroprotective effects through the upregulation of p-Akt expression, downregulation of p-ASK1, p-JNK3, and cleaved caspase-3 expression, and inhibition of neuronal apoptosis (Pei et al., 2016)