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Although GLP-1s alone cannot be the answer to Indias burgeoning epidemics of diabetes and obesity, they offer hope for many who are struggling with these conditions, especially since drug prices are expected to fall further by March or April

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Hexarelin, due to its very high GHS-R1a affinity, drives rapid receptor internalisation via GRK2--arrestin-2 pathways with GHS-R1a surface expression declining by 4452% after 5 consecutive daily doses at 10 g/kg in rat pituitary preparations

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