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Obesity: Excess body fat, especially abdominal fat, increases insulin resistance and impairs the ability of cells to use insulin effectively, and leads to elevated blood sugar levels

People have achieved an astounding amount of weight loss with tirzepatide, says Julie Ingelfinger, professor of pediatrics at Harvard Medical School, who co-authored an editorial accompanying the recent SURMOUNT-1 trial on the impact of the drug on 2,539 people without diabetes

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Antioxidants, such as glutathione, donate electrons to free radicals

This raises an intriguing question: could GLP-1based therapies benefit individuals with behavioral or mental health disorders even in the absence of overt metabolic disease