Crucially, besides inducing membrane depolarization through 7nAChR-gated Ca2+ conductance, there is growing evidence suggesting potential metabotropic activities of this ionotropic receptor [43]
Cox GF, Sleeper LA, Lowe AM et al : Factors associated with establishing a causal diagnosis for children with cardiomyopathy
An Australian study estimated that nearly one in five future TC cases could be attributed to current overweight or obesity [195]
For decades, it has been used clinically around the world to treat chronic viral infections, immune deficiency states, and as an adjunct in cancer treatment
On the one hand, its activation can promote cancer progression, invasion, metastasis, and resistance to chemotherapeutic agents [68]