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This is a known concern with GLP-1 medications, and tirzepatide and bone loss is an active area of research

Cayenne Extract (4:1) 500mg: Highly concentrated natural product that increases energy expenditure, calorie loss, stimulates carbohydrate oxidation, burns carbohydrates, helps protect the stomach in case of ingestion of irritating substances, contributes to weight reduction and helps in weight loss programmes

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Study: Tirzepatide against obesity and insulin-resistance: pathophysiological aspects and clinical evidence