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iScience 23 , 101681 (2020)

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Clinical evidence: Research published in the European Journal of Nutrition demonstrated that IV glutathione significantly increased plasma antioxidant capacity and skin lightening markers in participants over a four-week protocol (Weschawalit et al., 2017)

Indeed, it was recently reported that treatment of cells with H 2 O 2 , which can lower GSH levels, leads to increased expression of NRF2 target genes in a KEAP1-independent mechanism 69