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The jump from 1mg to 4mg produced nearly double the weight loss, from 8.7% to 17.1%, suggesting that the glucagon component only becomes meaningfully active somewhere in that dose range

Motor problems in Prader-Willi syndrome: a systematic review on body composition and neuromuscular functioning

Accessed April 2, 2024

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Thats the palmitoyl part, which makes it fat-soluble so it can actually penetrate