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When NF-kB translocates to the cell nucleus, it switches on the transcription of pro-inflammatory cytokines including TNF-alpha, IL-6, and IL-1-beta
The main intracellular antioxidant enzymes participating in the protection of cells against the damaging effects of ROS are glutathione peroxidase (GPx) and superoxide dismutase (SOD) (6, 7)
*Corresponding Author: Wujie Xia Department of Cardiology, The Second Affiliated Hospital and Yuying Childrens Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China [email protected] E-mail: This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms Abstract Glutathione is an important antioxidant that plays an important role in myocardial remodeling
Insomnia can be linked to stress, pain, shift work, caffeine, untreated sleep apnea, restless legs, depression, anxiety, medication effects, or withdrawal