STRUCTURE Glutathione is a tripeptide consisting of three amino acids: glutamate, cysteine, and glycine, hence, described as -l-glutamyl-l-cysteinylglycine [Figure 1].[] INTRACELLULAR DISTRIBUTION OF GLUTATHIONE Glutathione is synthesized from glutamate, cysteine, and glycine in the cytosol
In addition, butylmalonate, an inhibitor of DIC, significantly decreased mGSH, suggesting DIC as the major GSH transporter in mouse cerebral cortical mitochondria (Kamga et al., 2010)
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Mice were maintained on a standard diet, and water was freely available
N-acetylcysteine improves liver function in patients with non-alcoholic fatty liver disease