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Animal models of autism: a perspective from autophagy mechanisms
Usually, a high dose is given first, then a lower dose is used to keep levels up
Cryogenic electron microscopy (cryoEM) structural analyses revealed that E27 replaces endogenous CRL4 substrate receptors, resulting in proper positioning of STAT2 for polyubiquitylation and subsequent proteasomal destruction to inhibit host IFN signalling
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