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Studies of bariatric surgery patients have documented similar phenomena, where rapid weight changes can temporarily exacerbate joint symptoms before eventual improvement occurs

These include: Gastrointestinal discomfort : Nausea, stomach upset, or diarrhea may occur in some cases

If you feel unusually cold after starting GLP-1 treatment, comfort measures such as layering clothing, drinking warm fluids and keeping active may help

Among the responders who continued treatment to 6 months, about 71% reported normal menses

Translating Results to Pounds For men at various starting weights, using the 15% average: Starting at 220 pounds: Average expected loss: 33 pounds End weight: 187 pounds High responder (20%+): Could reach 176 pounds or lower Starting at 250 pounds: Average expected loss: 37-38 pounds End weight: 212-213 pounds High responder: Could reach 200 pounds or lower Starting at 280 pounds: Average expected loss: 42 pounds End weight: 238 pounds High responder: Could reach 224 pounds or lower Starting at 300 pounds: Average expected loss: 45 pounds End weight: 255 pounds High responder: Could reach 240 pounds or lower These are approximations based on average results