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Antioxidants, 10(3), 364

Although the rates of gallstone-related hospitalization were relatively low in both groups, at 1.5% per year in those on the very-low-calorie diet and 0.4% per year in those on the low-calorie diet, the results suggest that the health benefits of weight loss may be best achieved through modest calorie restriction (Johansson 2014)

3 Moreover, it supports immune function by serving as an energy source for immune cells like lymphocytes and macrophages