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A recent study demonstrated that the ability of a p53 variant, a nonsynonymous single-nucleotide polymorphism referred to as P47S found in people of African descent, to transactivate GLS2 was impaired [120, 126]

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At the March committee meeting, Kinsley said the cost to the state for GLP-1 coverage would be "is in the range of zero to 10 million in state dollars, which is much cheaper than a lot of the costs of cardiovascular disease." According to the NCDHHS statement, which was issued to WUNC on Thursday, "...the current estimate to cover GLP-1s is approximately $16 million annually