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Nat Neurosci 3 : 11071112

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Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling

FOXO4-DRI causes nuclear exclusion of active p53 and induces apoptosis in senescent TM3 Leydig cells Immunofluorescent staining showed elevated levels of Ser15-phospho-p53 in the nucleus of senescent TM3 Leydig cells (Figure 5A)

5-amino 1MQ or another variation could be promising to treat a variety of other diseases