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Explain the effect of changes of Vd & Cl on the duration of drug action (t1/2)
PAs direct effects on the CNS are not fully clear, with some studies suggesting it might have mild neuroprotective effects, while others indicate it induces inflammation [35, 36]
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Its location matters because visceral fat drains directly into the liver through the portal vein, meaning the fatty acids and inflammatory signals it releases reach the liver first and at high concentration.Dr
Likewise, when analyzing the developmental dynamics in human embryos, we found that they seem to better withstand the maternal to embryonic transition which reaches its peak at D3 of development (Vassena et al., 2011)
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