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2 Substance evaluation cases agreed in advance (written procedure) MSC had already agreed several draft decisions under written procedure, including the following substances: Bis(2-propylheptyl) phthalate (EC 258-469-4) 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one (EC 216-133-4) 2-Propenoic acid, methyl ester, reaction products with mixed O,O-bis(branched and linear pentyl and iso-Bu) phosphorodithioates (EC 300-340-2) 4,4'-isopropylidenebis[2-allylphenol] (EC 217-121-1) 3 Dossier evaluation decisions also progressed Under dossier evaluation, MSC agreed cases including: Amines, C36-alkylenedi- (EC 273-282-8) Pivalic acid (EC 200-922-5) (Plus one compliance check case listed as confidential.) 4 Ad hoc Working Group established on SVHC ELoC cases (Art

Innovent Biologics launched its GLP-1 drug mazdutide in 2025 and has already secured approval for obesity ahead of some rivals, underscoring the importance of the weight-loss market

Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, including glucose metabolism, insulin signaling, and gastrointestinal function

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Acetylation of p53 at K320 activates CDKN1A/p21, thereby delaying ferroptosis (Ji et al., 2021)