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Excess supplementation may alter detoxification pathways or electrolyte balance, potentially worsening organ stress if not medically supervised

Given that exercise and tDCS share common neural substrates, it is hypothesised that combining these techniques produces synergistic effects, yielding cognitive enhancement outcomes superior to those of single interventions

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*Correspondence: Arjola Bano, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers