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In humans, methimazole has a long residence time in the thyroid gland and can exert antithyroid effects for 24 hours or more

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Visualize steady state, clearance curves, and dose comparisons

Nevertheless, in addition to increasing the expression of genes involved in mitochondrial -oxidation, cooperation can also occur between mitochondria and peroxisomes as an adaptive mechanism to facilitate -oxidation in mammals ( Reference Van den Branden and Vamecq 57 , Reference Mannaerts, Debeer and Thomas 58 )

Grunwell, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Childrens Healthcare of Atlanta at Egleston, Emory University School of Medicine, 1405 Clifton Rd