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Conversely, conditional KO of HMGB1 in rods restored the thickness of the ONL, yet had no effect on the mobilization and activation of macrophages typically seen following retinal detachment, suggesting the potential involvement of other DAMPs in the process (33)

For gene expression profiling, total RNA of GFP or NRF2 expressing Hs 578 T cells was purified using EuroGOLD TriFast (Euroclone, Milan, Italy)