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In addition, we have reported that GLP-1/exendin-4 treatment inhibits the activities of AMPK and S6K1 when the activation of these protein kinases peak in both the VMH and LH areas

10.1038/nri.2016.123 Nat

GLP-1 is a gut hormone that the body naturally releases after eating to help reduce blood sugar levels

To further evaluate the reliability of the evidence, we assessed the degree of overlap among systematic reviews using the CCA method (Supplementary data 4)